Autologous fat grafting is considered to be an ideal filler, as adipose tissues contain an abundant source of regenerative multipotent cells (preadipocytes, mesenchymal stem cells, etc.).
To diminish partial resorption of FAT, A-PRP is mixed with the harvested fat cells.

Large quantities of growth factors (PDGF, TGF, IGF, EGF, VEGF, FGF) involved in stem cell proliferation, differentiation. Fibroblast and endothelial cells contribute to fat graft survival.


RegenKit Extracell Adipocytes is designed to collect, wash and combine the patient’s adipose tissue with their own platelet rich plasma.

RegenKit Extracell Adipocytes - Medical Device Class IIb - CE0086

Intended Use: Preparation of autologous platelet rich plasma (A-PRP) and other plasma-derived product.


In vitro studies have shown that 20% autologous, non-activated, PRP (nPRP) represent a safe, efficient, and cost-effective medium supplement for adipose-derived mesenchymal stem cell (AT-MSC) expansion.

Consequently, PRP should be considered as an alternative to fetal bovine serum (FBS) or other non-autologous blood derivatives in cell cultures.1

In vivo studies have shown that FAT & PRP combined diminishes post transplantation fat resorption, optimises fat graft survival, increases cell proliferation, and makes injections easier with less fat nodules.2-5
Therefore, Regen Lab has designed a kit dedicated to the combination of adipose tissue and Platelet Rich Plasma (PRP): the RegenExtracell® Adipocyte kit.


  1. Atashi F. et al. Autologous platelet-rich plasma: a biological supplement to enhance adipose-derived mesenchymal stem cell expansion. Tissue Engineering Part C Methods 2015; 21(3):253-62.
  2. Di Rienzo Businco L. et al. New technologies for the prevention and treatment of empty nose syndrome: minimally invasive and regenerative surgery with PRL. Aesthetic Medicin 2016; 2(1): 25-32
  3. Di Rienzo Businco L. et al. Functional reconstruction of turbinates with growth factors and adipose tissue in the treatment of empty nose syndrome. Jacobs Journal of Bone Marrow and Stem Cells Research 2015; 1(2): 009.
  4. Modarressi A. et al. Platelet Rich Plasma (PRP) improves fat grafting outcomes. World Journal of Plastic Surgery 2013; 2(1): 6-13.
  5. Tolba A. M. et al. Initial experience of face augmentation using fat graft-platelet rich plasma mix. Surgical Science 2015; 6: 489-498.
1. Marx RE.Platelet-richplasma: evidence to support its use. J Oral Maxillofac Surg 2004;62:489-96.
2- Abuaf, Yildiz H, Baloglu H, Bilgili ME, Simsek HA, Dogan B. Histologic Evidence of New Collagen Formulation UsingPlateletRichPlasmain Skin Rejuvenation: A Prospective Controlled Clinical Study. Ann
3- Cho JM, Lee YH, Baek RM, Lee SW. Effect ofplatelet-richplasmaon ultraviolet b-induced skin wrinkles in nude mice. J Plast Reconstr Aesthet Surg 2011;64:e31-e39.
Dermatol 2016;28:718-24.
4- Barone M, Tenna S, Cogliandro A, Panasiti V, Nobile C, Persichetti P. Application of regenerative medicine in treatment of acne scars. Plast Aesthet Res 2016;3:235-9.
5- Redaelli A. Face and Neck Revitalization WithPlatelet-richPlasma. Journal of Drugs in Dermatology 2010;9:466-72.
6- Fouque L. PRP & LED. Proceedings BioBridge Generation Regeneration Congress, 2014.
7- Lubin S. Improving the look and feel of keloid scars withPlateletRichPlasmavia microneedling technique. Proceedings BioBridge Generation Regeneration Congress, 2016.
8- Goisis M, Di Petrillo A, Rinna C, Brillante C, Guareschi M, Youssef DA. Fillers in Aesthetis Medicine. In: Injections in Aesthetic Medicine: Springer; 2014:3-24.
9- Goisis M, Stella E, Di Petrillo A. Malar Area. In: Injections in Aesthetic Medicine: Springer; 2014:73-88. These claims and indications of use have been reported in a number of cases during the Biobridge Conferences of 2013, 2014 and 2016.
For more information please contact our scientific team.

Skin Texture & Elasticity
A-PRP increases revascularisation, neo-callagenesis, tone, skin thickness and elasticity. It can be used as a standalone treatment or as a multi-treatment protocol combining technologies such as fractional laser, LED, chemical peels, dermal fillers, dermabrasion etc.6
Fibroblast proliferation is increased in the A-PRP group. This results in a doubling of the amount of collagen available within the extracellular matrix.3

The Patient’sPlatelet-RichPlasmastimulates cells to regenerate the skin’s connective tissue, resulting in accelerated healing post laser and chemical peels. It also improves the elasticity, tone and thickness of the skin and contributes to the remodelling of collagen fibres. 4-5
Examination of treated regions with A-PRP show new collagen formation, revascularisation, Glycosaminoglycans augmentation and anti-oxidant effect.6
Scars - Acne Scars
Treated scars have a noticeable improvement in colour, size and firmness. The use of A-PRP associated with microneedling is an innovative and represents a promising therapeutic treatment option for the management of keloid and pitted acne scars.7
Wrinkles & Dark Circles
RegenACR PLUS completes the RegenACR Kits line for the preparation of A-PRP® in Aesthetics, offering the exclusive PLUS technology for small to medium treated areas. 5,8,9

The combination of the patient’sPlateletRichPlasmaand its natural activator, Autologous Thrombin Serum (ATS) induces the formation of a biological glue and a three dimensional matrix, 100 % autologous. 8,9

Plateletsare stabilised at the treatment site for a long lasting growth factor delivery. 8,9
A-PRP delivery to the dermo-reticular area of the keloid scar allows for re-organisation of the tissues and decreasing mast cell proliferation and histamine release.7