What is A-PRP®?

The patient’s platelet concentrate prepared with RegenKit®

Platelets are key factors in hard and soft tissue repair mechanisms. They provide essential growth factors, such as FGF, PDGF, TGF-ß, EGF, VEGF, which are involved in stem cell migration, differentiation and proliferation. They also stimulate fibroblasts and endothelial cells to induce respectively new extracellular matrix deposition and neovascularization. The platelets are concentrated from the patient’s own blood plasma.

Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors such as IGF and HGF, and proteins. Among the plasma proteins, there are vital molecules for the coagulation process and generation of the fibrin polymer that will serve as a scaffold for cell migration and new tissue generation.

MECHANISM OF ACTION:
  1. Formation of tridimensional fibrin network.
  2. Release of chemo-attractants by leukocytes and platelets present in the network
  3. Migration of macrophages and stem cells
  4. Stem cell proliferation
  5. Stem cell differentiation into different cell types needed for tissue restoration
ILLUSTRATON OF A-PRP BENEFITS IN THE HEALING CASCADE
RegenKit BCT is CE Marked and is only available through authorized distributors. The Product has not been approved or cleared for marketing by the United States Food & Drug Administration.