Platelets are key factors in hard and soft tissue repair mechanisms. They provide essential growth factors, such as FGF, PDGF, TGF-ß, EGF, VEGF, which are involved in stem cell migration, differentiation and proliferation. They also stimulate fibroblasts and endothelial cells to induce respectively new extracellular matrix deposition and neovascularization. The platelets are concentrated from the patient’s own blood plasma.
Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors such as IGF and HGF, and proteins. Among the plasma proteins, there are vital molecules for the coagulation process and generation of the fibrin polymer that will serve as a scaffold for cell migration and new tissue generation.