5 to 10 ml
Bone marrow concentrate (bmc) is an autologous cell concentrate from bone marrow aspirate.
Bone marrow is a liquid tissue rich in a heterogeneous population of mature cells and multipotent stem cells.
Among them, the mesenchymal stromal cells (MSC) are the musculoskeletal tissue precursor cells.
RegenKit® Extracell BMC kits are specifically designed for the effective processing of bone marrow aspirate (BMA) by a short centrifugation in RegenTHT tubes. These tubes contain a biologically inert separating gel with a specific density that physically separates the plasma and the mononuclear cell (MNC) fraction, which contains the MSC, from the other bone marrow cellular elements.
More than 80% of the MSC are recovered in the resulting cell concentrate1. In vitro, these cells give rise to fibroblast colony-forming units (CFU-F) capable of undergoing osteogenesis, chondrogenesis and adipogenesis when cultured in their respective specific induction medium1.
Example of a procedure: Bone marrow was processed with the four tubes of the RegenKit® Extracell BMC.
The resulting BMC can be combined with platelet-rich plasma (RegenPRP) and autologous thrombin serum (ATS), prepared with RegenKit® Surgery, to obtain a gel.