The safe and effective leukocyte-reduced A PRP for musculoskeletal applications.
What is A-PRP ® ?
The patient’s platelet concentrate prepared with RegenACR® Kits
Platelets are key factors in hard and soft tissue repair mechanisms 1. They provide essential growth factors, such as FGF, PDGF, TGF-ß, EGF, VEGF, IGF, which are involved in stem cell migration, differentiation and proliferation. Additionally,platelets also stimulate fibroblasts and endothelial cells to induce new extracellular matrix deposition and neo-vascularisation respectively.
Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors (such as IGF and HGF), and proteins. Among theplasma proteins, the molecules vital for the coagulation process and for the fibrin polymer formation will serve as a scaffold for cell migration and new tissue generation.
5 to 6 ml
*BCT stands for Blood Cell Therapy
RegenKit® is composed of sterile disposable tubes, butterfly needle, transfer devices and syringes, packaged in a single-use double blister. RegenKit® cell separator gel allows for the easy, rapid and consistent preparation, from a small volume of blood, of A-PRP with an optimal platelet concentration and viability.
RegenKit® - Medical Device Class IIb - CE0086
Intended Use : Preparation of autologous platelet rich plasma (A-PRP) and other plasma-derived products.
In osteoarthritis of the knee, hip and shoulder, A-PRP® treatment resulted in improved functional outcomes and reduced pain in patients with early stage disease and has been shown to be markedly more effective than both hyaluronic acid and A-PRP prepared using a laboratory method. 2-6
A-PRP injection in chondropathy of the knee, hip, ankle and shoulder significantly improved the clinical outcomes over time. 2
In all treated sites, a trend of improvement compared to the pre-treatment period was observed, with p-values still significant compared to baseline at the final available follow-up at 3 years. 5
In tendinopathies, A-PRP® treatment provided significant clinical benefits in upto 90% of patients with continuous improvement over time with low levels of relapse and was found to be particularly effective in insertional tendinopathies. 7-11
Injection of A-PRP is a promising treatment option for sports injuries. This study showed a significant analgesic effect, even though the patients received only a single A-PRP injection. 8
Facet joints physiopathology can be caused by mechanical diseases, inflammatory issues or neuropathic diseases. 12-14
This clinical experience showed that at the end of follow-up period, A-PRP provided 38% decrease of Lower Back Pain, 81% decrease of LBP associated to Leg Pain, 43% decrease in RMQD score and 33% decrease in ODI score.13
A-PRP acts as an autologous antalgic and anti-inflammatory agent and is a valid alternative treatment to corticosteroids (especially for diabetic patients), since it is not harmful in the long term.13